Fabrication and Characterization of PVA Tricalcium Phosphate and Quercetin-doped Strontium Membranes for Guided Bone Regeneration

Guided Bone Regeneration (GBR) is a technique used in reconstructive dentistry to address small defects around dental implants and to facilitate bone regeneration in alveolar defects.It involves the use of bone grafts and barrier membranes to promote the selective growth of bone tissue while preventing soft tissue infiltration.Surface structural morphology analysis using scanning electron microscopy (SEM) revealed notable differences between the fabricated membrane samples.A comparative assessment indicated an increase in both porosity and nanofiber size upon the addition of strontium nanoparticles.This alteration was further corroborated by the observed decrease in hydrophilicity, as evidenced by an increase in the contact angle from the typical 30 degrees to 58.7 degrees.Our study offers a promising avenue for advancing guided bone regeneration through the development of PVA-TCP membranes tailored with quercetin and strontium.