The NLR, PLR, LMR Ratios in Venous Thromboembolism (VTE): A Study on Patients Affected by VTE with Active Cancer Compared to N0on-VTE

There is increased interest in new biomarkers when suspecting Venous Thromboembolism (VTE). A number of biomarkers can help elucidate the relationship between inflammation and VTE. This study focuses on the platelet-to-Lymphocyte Ratio (PLR), the Neutrophil-to-Lymphocyte ratio (NLR) and the monocyte-to-HDL cholesterol ratio (MHR) in patients affected by VTE (pulmonary embolism = PE, deep vein thrombosis = DVT, both diseases = PE+DVT). VTE patients with or without active cancer and patients unaffected by VTE were considered. NLR, PLR and LMR were higher in VTE patients than in non-VTEs. Differences were statistically significant. ( ). Remove brackets In VTEs with active cancer the NLR alone was higher compared to VTE patients without cancer. NLR was higher in PE patients, and LMR was higher in PE+DVTs. ROC curve analysis was unable to predict NLR to suspect PE. NLR could be a helpful biomarker in the decision-making process for VTE and PE in addition to already approved markers (D-dimer) to avoid inappropriate and expensive procedures.