Factors Influencing the Duration of Maintenance Therapy in Metastatic Colorectal Cancer

Duration of maintenance therapy is determined by the initial patient and colorectal cancer characteristics. However, it is significantly increased by local treatment of liver metastases. By reducing the tumour burden, a triplet induction chemotherapy regimen increases the rate of liver metastase resection.

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Publication Details

Journal
Cancers
Published
2024-12-30
DOI
https://doi.org/10.3390/cancers17010088
Primary Topic
Colorectal Cancer Treatments and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Factors Influencing the Duration of Maintenance Therapy in Metastatic Colorectal Cancer

Rémi Palmier, Caroline Truntzer, Thomas Rabel, François Ghiringhelli et al.
Cancers
Colorectal Cancer Treatments and Studies
article

Factors Influencing the Duration of Maintenance Therapy in Metastatic Colorectal Cancer

Rémi Palmier, Caroline Truntzer, Thomas Rabel, François Ghiringhelli, Julie Vincent, David Orry, Valentin Dérangère, Audrey Hennequin, Leïla Bengrine-Lefèvre, Morgane Peroz, Théo Fourrier
article en

Abstract

Duration of maintenance therapy is determined by the initial patient and colorectal cancer characteristics. However, it is significantly increased by local treatment of liver metastases. By reducing the tumour burden, a triplet induction chemotherapy regimen increases the rate of liver metastase resection.

CancersVol. 17(1)
Inserm (FR), Université de Bourgogne (FR), Centre Georges François Leclerc (FR), Centre de recherche Translationnelle en Médecine moléculaire (FR)
Good health and well-being
Openalex Percentile: Top 58%
Colorectal Cancer Treatments and Studies
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