Exploring the Link Between Obligate Anaerobe-Related Dysbiosis and Prostate Cancer Development: A Pilot Study
These findings suggest that OA-related dysbiosis may contribute to elevated PSA levels through prostate cell damage even before prostate cancer develops, possibly playing a role in chronic inflammation and the hypervascular changes seen in precancerous lesions. Future clinical trials with larger cohorts are needed to further evaluate the role of OA in prostate cancer development and progression.
Authors
- Belinda Nedjai (ORCID: https://orcid.org/0000-0001-8711-4577)
- Frank Chinegwundoh (ORCID: https://orcid.org/0000-0002-7466-7225)
- Emily F. Lane (ORCID: https://orcid.org/0000-0002-9286-5145)
- Greg L. Shaw (ORCID: https://orcid.org/0000-0003-3480-2100)
- Mark Wilks (ORCID: https://orcid.org/0000-0002-2170-1944)
- R.T.D. Oliver (ORCID: https://orcid.org/0000-0002-7879-8943)
- Efthymios Ladoukakis (ORCID: https://orcid.org/0000-0002-4807-1292)
Institutions
- Queen Mary University of London (GB)
- University College London (GB)
Publication Details
- Journal
- Cancers
- Published
- 2024-12-29
- DOI
- https://doi.org/10.3390/cancers17010070
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.47