Inhibition of triple-negative breast cancer growth via delphinidin-mediated suppression of the JAK2/STAT3/PD-L1 pathway
Dp may exert its anti-TNBC effects by downregulating PD-L1 expression in TNBC cells and exosomes through the JAK2/STAT3 signaling pathway, potentially restoring T cell activity and modifying the tumor microenvironment.
Authors
- Lujie Zheng (ORCID: https://orcid.org/0009-0003-8720-4400)
- Xiaoping Yu (ORCID: https://orcid.org/0009-0002-0367-1398)
- Fengcheng Deng
- Zheng Xiong (ORCID: https://orcid.org/0000-0001-5506-0199)
- Jiali Yan (ORCID: https://orcid.org/0000-0003-0295-6594)
- Yan Luo
- Xiaolong Song
- Yanfeng Zhu (ORCID: https://orcid.org/0000-0002-5198-5941)
Institutions
- Chengdu Medical College (CN)
- Chengdu University (CN)
- Seventh People's Hospital of Shanghai (CN)
Publication Details
- Journal
- Food & Nutrition Research
- Published
- 2024-12-31
- DOI
- https://doi.org/10.29219/fnr.v68.10974
- Citations
- 9
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.10
Funders
- Chengdu Medical College
- National Natural Science Foundation of China
- Natural Science Foundation of Sichuan Province