Humoral and cellular response to SARS-CoV-2 mRNA vaccine in paediatric heart transplant recipients

HTR had humoral response after vaccination, although they showed lower levels of specific anti-S antibodies compared to HC. There were no significant differences in the SARS-CoV2-specific cellular response between the two groups. Obtaining satisfactory data on this type of response could potentially challenge the current vaccine guideline recommendations.

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Publication Details

Journal
Heliyon
Published
2024-12-31
DOI
https://doi.org/10.1016/j.heliyon.2024.e41584
Citations
2
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.78

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article

Humoral and cellular response to SARS-CoV-2 mRNA vaccine in paediatric heart transplant recipients

Manuela Camino López, Begoña Santiago, Amanda Bermejo, Roberto Alonso et al.
2 citations
Heliyon
SARS-CoV-2 and COVID-19 Research
0.78
article

Humoral and cellular response to SARS-CoV-2 mRNA vaccine in paediatric heart transplant recipients

Manuela Camino López, Begoña Santiago, Amanda Bermejo, Roberto Alonso, María Ángeles Muñoz‐Fernández, Alicia Hernanz‐Lobo, Laura Tarancón‐Díez, Beatriz Lazaro-Martin, Nuria Gil Villanueva, María Luisa Navarro Gómez
article en
2 citations

Abstract

HTR had humoral response after vaccination, although they showed lower levels of specific anti-S antibodies compared to HC. There were no significant differences in the SARS-CoV2-specific cellular response between the two groups. Obtaining satisfactory data on this type of response could potentially challenge the current vaccine guideline recommendations.

HeliyonVol. 11(1)
Universidad Complutense de Madrid (ES), Instituto de Salud Carlos III (ES), Hospital General Universitario Gregorio Marañón (ES), Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES), Centre for Biomedical Network Research on Rare Diseases (ES)
European Society for Paediatric Infectious Diseases, Ministerio de Ciencia e Innovación, Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, Instituto de Investigación Sanitaria Gregorio Marañón, Instituto de Salud Carlos III
Zero hunger
Openalex Percentile: Top 25%
SARS-CoV-2 and COVID-19 Research
0.78
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Humoral and cellular response to SARS-CoV-2 mRNA vaccine in paediatric heart transplant recipients — Manuela Camino López, Begoña Santiago, et al. · Heliyon (2024) | TGRS Research Map | TGRS