Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma

Our study deciphers the proteomics landscape in human melanoma, providing important information on the tumour microenvironment and identifying SIRT1 as having important prognostic and therapeutic implications.

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Publication Details

Journal
British Journal of Dermatology
Published
2024-12-31
DOI
https://doi.org/10.1093/bjd/ljae433
Citations
6
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
1.70

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article

Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma

Fang Zhao, Lars Borgards, Christoph Krisp, Devon Siemes et al.
6 citations
British Journal of Dermatology
Cancer Immunotherapy and Biomarkers
1.70
article

Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma

Fang Zhao, Lars Borgards, Christoph Krisp, Devon Siemes, Renáta Váraljai, Batool Shannan, Alexander Roesch, Philippa Spangenberg, Dirk Schadendorf, Florian Rambow, Iris Helfrich, Alpaslan Tasdogan, Franziska Hoffmann, Selma Ugurel, Daniel Robert Engel, Camille Soun, Ferdinand von Eggeling, Sarah Scharfenberg, Hartmut Schlueter, Jenny Bottek, Jan-Malte Placke, Anette Paschen
article en
6 citations

Abstract

Our study deciphers the proteomics landscape in human melanoma, providing important information on the tumour microenvironment and identifying SIRT1 as having important prognostic and therapeutic implications.

British Journal of DermatologyVol. 192(3)
Universität Hamburg (DE), German Cancer Research Center (DE), University Medical Center Hamburg-Eppendorf (DE), Essen University Hospital (DE), Jena University Hospital (DE), University of Duisburg-Essen (DE), Ludwig-Maximilians-Universität München (DE)
Deutsche Forschungsgemeinschaft, Bristol-Myers Squibb Canada
Good health and well-being
Openalex Percentile: Top 12%
Cancer Immunotherapy and Biomarkers
1.70
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