Identification of RAD51AP1 as a key gene in hepatitis B virus-associated hepatocellular carcinoma
The LINC01419/miR-8070/RAD51AP1 axis promotes the HBV-associated HCC progression through an HBV-boosted positive feedback loop and Wnt/β-catenin signaling. These findings provide novel insights into the underlying mechanisms and may offer potential diagnostic and therapeutic targets in HBV-associated HCC.
Authors
- Changfeng Sun (ORCID: https://orcid.org/0000-0001-8648-8120)
- Meiling Wan (ORCID: https://orcid.org/0009-0005-2434-7759)
- Xiaoling Liu (ORCID: https://orcid.org/0000-0002-7665-337X)
- Cunliang Deng
- Yonghong Wang (ORCID: https://orcid.org/0009-0004-5413-8627)
- Yaling Li (ORCID: https://orcid.org/0000-0002-1477-5005)
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e41594
- Citations
- 3
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- Sichuan Province Science and Technology Support Program