<scp>BLOC1S1</scp> Control of Vacuolar Organelle Fidelity Modulates Murine <scp> T <sub>H</sub> 2 </scp> Cell Immunity and Allergy Susceptibility
BLOC1S1 depletion in mouse CD4<sup>+</sup> T cells mediated disruption of mitochondrial integrity to initiate a predominant T<sub>H</sub>2-responsive phenotype via STING-NF-κB-driven signaling of the canonical T<sub>H</sub>2 regulatory program.
Authors
- Christian A. Combs (ORCID: https://orcid.org/0000-0003-4656-4840)
- Stewart J. Levine (ORCID: https://orcid.org/0000-0001-9313-9746)
- Kaiyuan Wu (ORCID: https://orcid.org/0000-0001-7395-4524)
- Rahul Sharma (ORCID: https://orcid.org/0009-0001-3902-3547)
- Xianglan Yao (ORCID: https://orcid.org/0000-0003-0668-0353)
- Michael N. Sack (ORCID: https://orcid.org/0000-0002-3411-0000)
- Kim Han (ORCID: https://orcid.org/0000-0002-6415-8072)
- Pradeep K. Dagur
- Anna Chiara Russo (ORCID: https://orcid.org/0009-0007-3700-5963)
Institutions
- National Institutes of Health (US)
- National Heart, Lung, and Blood Institute (US)
- Pulmonary and Critical Care Associates (US)
Publication Details
- Journal
- Allergy
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1111/all.16461
- Citations
- 4
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Heart, Lung, and Blood Institute
- NHLBI Division of Intramural Research