Safety of Intermittent Parenteral Midazolam Injection in Hospitalized Patients Admitted to Non-Intensive Care Nursing Units: A Retrospective Matched-Cohort Study

The administration of parenteral midazolam in non-ICU nursing units resulted in a similar incidence of hypotension, bradycardia, bradypnea, escalation in oxygen requirement, and escalation in level of care compared with lorazepam. These results suggest that midazolam may have a similar safety profile to lorazepam, supporting its use in non-ICU nursing units.

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Publication Details

Journal
Annals of Pharmacotherapy
Published
2024-12-30
DOI
https://doi.org/10.1177/10600280241299059
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
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article

Safety of Intermittent Parenteral Midazolam Injection in Hospitalized Patients Admitted to Non-Intensive Care Nursing Units: A Retrospective Matched-Cohort Study

Richard R. Riker, David Gagnon, Nicolette Centanni, Haley Torr et al.
Annals of Pharmacotherapy
Intensive Care Unit Cognitive Disorders
article

Safety of Intermittent Parenteral Midazolam Injection in Hospitalized Patients Admitted to Non-Intensive Care Nursing Units: A Retrospective Matched-Cohort Study

Richard R. Riker, David Gagnon, Nicolette Centanni, Haley Torr, Ashley Gale, Maria M. Mills
article en

Abstract

The administration of parenteral midazolam in non-ICU nursing units resulted in a similar incidence of hypotension, bradycardia, bradypnea, escalation in oxygen requirement, and escalation in level of care compared with lorazepam. These results suggest that midazolam may have a similar safety profile to lorazepam, supporting its use in non-ICU nursing units.

Annals of PharmacotherapyVol. 59(7)
Tufts University (US), Maine Medical Center (US), MaineHealth (US)
Good health and well-being
Openalex Percentile: Top 68%
Intensive Care Unit Cognitive Disorders
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