YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway
YWHAG upregulates TMOD3 expression, leading to the activation of ERK1/2 phosphorylation in the MAPK pathway, thereby promoting the invasion and metastasis of bladder cancer cells.
Authors
- Zhenpeng Zhu (ORCID: https://orcid.org/0009-0000-4089-3374)
- Shiming He (ORCID: https://orcid.org/0000-0002-6586-9781)
- Yucai Wu (ORCID: https://orcid.org/0000-0003-0087-9548)
- Tai Tian
- Ninghan Feng (ORCID: https://orcid.org/0000-0002-0892-6102)
- Yuexian Guo (ORCID: https://orcid.org/0000-0003-3747-7067)
- Yanqing Gong
- Bao Guan (ORCID: https://orcid.org/0000-0003-0225-8681)
- Xuesong Li (ORCID: https://orcid.org/0009-0006-0039-2544)
- Wenzhi Gao (ORCID: https://orcid.org/0000-0002-5944-017X)
- Hao Han (ORCID: https://orcid.org/0000-0001-8035-9838)
- Jian Fan
- Aixiang Wang
Institutions
- Hebei Medical University (CN)
- Peking University (CN)
- Third Hospital of Hebei Medical University (CN)
- Wuxi No.2 People's Hospital (CN)
- Peking University First Hospital (CN)
- Wuxi People's Hospital (CN)
- Peking University Sixth Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1186/s12967-024-06003-y
- Citations
- 5
- Primary Topic
- 14-3-3 protein interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Peking University First Hospital
- National Natural Science Foundation of China
- Peking University