Facile Synthesis of Imidazo[1,2-a]pyridines via LED Light Induced Reaction between 2-Aminopyridines and Acetophenones

Imidazo[1,2-a]pyridines are class of privileged motifs present in various important drugs. The majority of the processes involve metal catalysts, despite the fact that there are substantial benefits to develop new methodologies for the synthesis of imidazo[1,2-a]pyridines. In this work, an eco-friendly method is reported for the synthesis of imidazo[1,2-a]pyridines in the presence of LED light source under ambient conditions. The reaction proceeds smoothly with both electron donating and electron withdrawing groups to afford the products in excellent yields.