Monoclonal Anti-CD47 Therapy and its Haematological Effects, including Anaemia and Thrombocytopenia

Monoclonal anti-CD47 therapy is a new form of immunotherapy, which has been used in a clinical setting in recent years for the treatment of haematological and solid malignancies. Anti-CD47 functions by blocking the CD47-SIRPα interaction and promotes the phagocytosis of cancer cells, which attempt to invade the immune systems mechanisms via this interface.

Publication Details

Journal
Emergency Medicine Trauma & Surgical Care
Published
2024-08-30
DOI
https://doi.org/10.24966/ets-8798/100070
Primary Topic
Phagocytosis and Immune Regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Monoclonal Anti-CD47 Therapy and its Haematological Effects, including Anaemia and Thrombocytopenia

Emergency Medicine Trauma & Surgical Care
Phagocytosis and Immune Regulation
article

Monoclonal Anti-CD47 Therapy and its Haematological Effects, including Anaemia and Thrombocytopenia

article en

Abstract

Monoclonal anti-CD47 therapy is a new form of immunotherapy, which has been used in a clinical setting in recent years for the treatment of haematological and solid malignancies. Anti-CD47 functions by blocking the CD47-SIRPα interaction and promotes the phagocytosis of cancer cells, which attempt to invade the immune systems mechanisms via this interface.

Emergency Medicine Trauma & Surgical CareVol. 10(1)
Openalex Percentile: Top 69%
Phagocytosis and Immune Regulation
DOIOpen Access PDFOpenAlex
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Monoclonal Anti-CD47 Therapy and its Haematological Effects, including Anaemia and Thrombocytopenia · Emergency Medicine Trauma & Surgical Care (2024) | TGRS Research Map | TGRS