Ivermectin Combined With Recombinant Methioninase (rMETase) Synergistically Eradicates MiaPaCa-2 Pancreatic Cancer Cells
The combination of ivermectin and rMETase effectively eradicated MiaPaCa-2 pancreatic cancer cells. The present results indicate the future clinical potential of the combination of rMETase, currently administered orally to patients as a dietary supplement, and oral ivermectin on pancreatic cancer.
Authors
- Michael Bouvet (ORCID: https://orcid.org/0000-0002-0086-2159)
- Shinji Miwa (ORCID: https://orcid.org/0000-0002-5962-8287)
- Byung Mo Kang (ORCID: https://orcid.org/0000-0003-0900-094X)
- Katsuhiro Hayashi (ORCID: https://orcid.org/0000-0001-8665-2154)
- Norio Yamamoto (ORCID: https://orcid.org/0000-0002-7250-625X)
- Takashi Higuchi (ORCID: https://orcid.org/0000-0003-2896-4939)
- Hiroyuki Tsuchiya (ORCID: https://orcid.org/0000-0003-0730-7921)
- KOHEI MIZUTA
- Satoru Demura
- Kentaro Igarashi (ORCID: https://orcid.org/0000-0003-2278-1736)
- Sei Morinaga (ORCID: https://orcid.org/0000-0003-2961-9432)
- Hiroaki Kimura (ORCID: https://orcid.org/0000-0003-2145-8726)
- Robert M. Hoffman
- Qinghong Han
Institutions
- Kanazawa University (JP)
- University of California San Diego (US)
- AntiCancer (United States) (US)
Publication Details
- Journal
- Anticancer Research
- Published
- 2024-12-30
- DOI
- https://doi.org/10.21873/anticanres.17396
- Citations
- 3
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16