Comprehensive evaluation of genomic and functional assays for homologous recombination deficiency with high-grade epithelial ovarian cancer: Platinum sensitivity and prognosis
Genomic scar score, given by AmoyDx HRD Complete Panel, was most associated with the efficacy of platinum treatment in patients with high-grade ovarian cancer. Validation is warranted via prospective studies.
Authors
- Xiaotian Zhang (ORCID: https://orcid.org/0000-0003-1167-3035)
- Xingzhu Ju (ORCID: https://orcid.org/0000-0002-4508-2025)
- Xiaohua Wu (ORCID: https://orcid.org/0000-0002-7664-8327)
- Qinhao Guo (ORCID: https://orcid.org/0000-0003-4661-481X)
- Zheng Feng
- Hao Wen (ORCID: https://orcid.org/0000-0002-9587-8742)
- Li Xing (ORCID: https://orcid.org/0000-0002-4186-7909)
- Zhan Huang
- Changbin Zhu
Institutions
- Fudan University Shanghai Cancer Center (CN)
- Dian Diagnostics (China) (CN)
Publication Details
- Journal
- International Journal of Gynecological Cancer
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1016/j.ijgc.2024.100031
- Citations
- 2
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.57