Comparing Immuno-oncology Combination Therapy With Tyrosine Kinase Inhibitor Monotherapy for Advanced Renal Cell Carcinoma

We demonstrated the advantage of IO-TKI combination therapy compared to TKI monotherapy in real-world clinical settings. However, in IMDC favorable patients PFS and OS did not significantly differ to TKI monotherapy. This may indicate the need for caution when selecting treatment options for IMDC favorable-risk patients.

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Publication Details

Journal
Anticancer Research
Published
2024-12-30
DOI
https://doi.org/10.21873/anticanres.17426
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

Comparing Immuno-oncology Combination Therapy With Tyrosine Kinase Inhibitor Monotherapy for Advanced Renal Cell Carcinoma

Takemura Ayana, Keita Tamura, Kyohei Watanabe, YUTO MATSUSHITA et al.
17 links
Anticancer Research
Renal cell carcinoma treatment
article

Comparing Immuno-oncology Combination Therapy With Tyrosine Kinase Inhibitor Monotherapy for Advanced Renal Cell Carcinoma

Takemura Ayana, Keita Tamura, Kyohei Watanabe, YUTO MATSUSHITA, Atsushi Otsuka, Gaku Ishikawa, Teruo Inamoto, Daisuke Motoyama, Hiromitsu Watanabe, Y. Tsuchiya, Shunsuke Watanabe, SANO ASUKA
article en

Abstract

We demonstrated the advantage of IO-TKI combination therapy compared to TKI monotherapy in real-world clinical settings. However, in IMDC favorable patients PFS and OS did not significantly differ to TKI monotherapy. This may indicate the need for caution when selecting treatment options for IMDC favorable-risk patients.

Anticancer ResearchVol. 45(1)
Hamamatsu University School of Medicine (JP)
Good health and well-being
Openalex Percentile: Top 56%
Renal cell carcinoma treatment
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Comparing Immuno-oncology Combination Therapy With Tyrosine Kinase Inhibitor Monotherapy for Advanced Renal Cell Carcinoma — Takemura Ayana, Keita Tamura, et al. · Anticancer Research (2024) | TGRS Research Map | TGRS