SLC7A11/xCT-mediated Cystine Uptake Regulates Intracellular Glutathione and Promotes Antioxidant Defense in Lymphatic Endothelial Cells
xCT functions as a cystine transporter, contributing to increased GSH levels in lymphatic fluid in melanoma metastasis.
Authors
- Shiho Hashiguchi (ORCID: https://orcid.org/0000-0001-8943-649X)
- Shohta Kodama
- Seiji Kondo (ORCID: https://orcid.org/0000-0001-9341-5069)
- Tomoko Tanaka (ORCID: https://orcid.org/0000-0002-3826-3653)
- Ryosuke Mano (ORCID: https://orcid.org/0000-0003-3514-8200)
Institutions
- Fukuoka University (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2024-12-30
- DOI
- https://doi.org/10.21873/anticanres.17393
- Citations
- 4
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- Fukuoka University