<i>In vitro</i> susceptibility of 147 international clinical <i>Mycobacterium abscessus</i> isolates to epetraborole and comparators by broth microdilution
Epetraborole demonstrated potent in vitro activity against M. abscessus with MICs from 0.03 to 0.25 mg/L and consistent activity against all subspecies, resistance phenotypes and morphotypes. These data support clinical evaluation of epetraborole as a therapeutic option for M. abscessus disease.
Authors
- Jakko van Ingen (ORCID: https://orcid.org/0000-0002-0581-2003)
- Minh-Vu H Nguyen (ORCID: https://orcid.org/0000-0001-7598-7362)
- Charles L. Daley (ORCID: https://orcid.org/0000-0003-3324-926X)
- Vinicius Calado Nogueira de Moura (ORCID: https://orcid.org/0000-0001-5874-0958)
- Tiffany R. Keepers
Institutions
- Radboud University Nijmegen (NL)
- University Medical Center (US)
- Radboud University Medical Center (NL)
- National Jewish Health (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1093/jac/dkae461
- Citations
- 2
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.77