Epigenetic Modulation with 5-Aza-CdR Prevents Metabolic-Associated Fatty Liver Disease Promoted by Maternal Overnutrition
5-Aza-CdR was shown to mitigate MAFLD features in offspring of maternal overnutrition by reversing DNA hypermethylation and improving metabolic pathways, though its dual impact on inflammation highlights the need for further research to optimize its therapeutic potential.
Authors
- Zhimin Liu (ORCID: https://orcid.org/0000-0002-9333-8101)
- Hui Peng (ORCID: https://orcid.org/0000-0002-8901-1384)
- Xian Wang (ORCID: https://orcid.org/0000-0003-4449-7939)
- Ke Zhang (ORCID: https://orcid.org/0009-0002-9053-4278)
- Jiangyuan Li (ORCID: https://orcid.org/0000-0001-9983-1119)
- Linglin Xie (ORCID: https://orcid.org/0000-0002-3502-5342)
- Henghui Cheng
- Jie Wu (ORCID: https://orcid.org/0000-0002-9877-1764)
Institutions
- Prevention Institute (US)
- Texas A&M University (US)
Publication Details
- Journal
- Nutrients
- Published
- 2024-12-30
- DOI
- https://doi.org/10.3390/nu17010106
- Citations
- 2
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 2.22