Ultrasound Features of Helicobacter pylori-Related Gastritis
<b>Background</b> Abdominal ultrasound (US) is a reliable method for visualizing gastric wall layers and measuring their thickness. The objective of this study is to characterize the ultrasound features of <i>H. pylori</i>-induced gastritis and assess its predictive potential role for this condition. <b>Methods</b> A cohort of 119 patients underwent gastroscopy with biopsy and abdominal US to evaluate antral wall thickness (AWT), submucosal wall thickness (SLT), mucosal wall thickness (MLT), gastric motility, and the presence of ingested material. They were divided into three groups: group A (normal mucosa without <i>H. pylori</i> infection), group B (gastritis <i>H. pylori</i> negative) and group C (gastritis <i>H. pylori</i> positive). <b>Results</b>: SLT and reduced gastric motility were significantly increased in the <i>H. pylori</i> gastritis group (<i>p</i> < 0.001). Multivariate analysis identified SLT as the only significant independent predictor of <i>H. pylori</i> gastritis (<i>p</i> < 0.001). An SLT threshold of 1.55 mm was determined as optimal for differentiating <i>H. pylori</i>-positive patients from -negative, yielding a sensitivity of 77% and a specificity of 72%. <b>Conclusions</b> These findings suggest that <i>H. pylori</i> gastritis is characterized by submucosal layer thickening and impaired gastric motility.
Authors
- Alfredo Di Leo (ORCID: https://orcid.org/0000-0003-2026-1200)
- Veronica Nassisi (ORCID: https://orcid.org/0000-0003-1003-8179)
- Francesco Cocomazzi (ORCID: https://orcid.org/0000-0002-6992-5875)
- Antonella Marra
- Fabrizio Bossa (ORCID: https://orcid.org/0000-0002-4518-9949)
- Giuseppe Losurdo (ORCID: https://orcid.org/0000-0001-7038-3287)
- Sonia Carparelli (ORCID: https://orcid.org/0000-0003-2054-8754)
- Maria Rosa Valvano (ORCID: https://orcid.org/0000-0003-4704-8354)
- Francesco Perri (ORCID: https://orcid.org/0000-0001-8314-8016)
- Fulvia Terracciano
- Chiara Lillo
Institutions
- University of Messina (IT)
- Casa Sollievo della Sofferenza (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Gastroenterology Hospital "Saverio de Bellis" (IT)
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Antibiotics
- Published
- 2024-12-28
- DOI
- https://doi.org/10.3390/antibiotics14010012
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00