Psycho-neuro-immuno-endocrinology: Study of the key factors of disease creation

Human civilization proceeded along with the development of the brain, both in size and activities.The development of a very strong power of thinking is also associated with the development of high ambitions and frustrations.Failure to tackle the adversities of life can affect the power of thinking, and it creates a stressful condition in the mind, termed psychological stressors [1,2,3].The term Psycho-Neuro-Immuno-Endocrinology (PNIE) was first described in 1936, though such effects of psychology on health have been noticed since ancient times and documented in different cultures.It covers the study of interactions between different psychological factors with physiological processes like neuronal, endocrine, and immune responses [1,4,5].Thus, the