The Bioefficacy Protocol: biomarkers identification of TNF inhibitors efficacy in axial spondyloarthritis patients using transcriptome and proteome analysis
This project's innovative approach lies in identifying potential biomarkers for TNFi (Adalimumab) response at baseline, paving the way for advancements in precision medicine in this field. Additionally, it seeks to establish evidence of the therapy's impact on gene and protein expression, offering deeper insights into the pathophysiological mechanisms underlying the therapeutic response.
Authors
- Fernando Pimentel‐Santos (ORCID: https://orcid.org/0000-0002-2816-7705)
- Jaime Branco (ORCID: https://orcid.org/0000-0001-7024-4375)
- Ana Varela Coelho (ORCID: https://orcid.org/0000-0002-6143-4203)
- Daniel Sobral (ORCID: https://orcid.org/0000-0003-3955-0117)
- Rita Pinheiro Torres (ORCID: https://orcid.org/0000-0001-7090-7925)
- Ana Filipa Fernandes (ORCID: https://orcid.org/0000-0002-5579-2629)
- Sara Maia (ORCID: https://orcid.org/0000-0001-8638-0566)
Institutions
- Hospital Center of Cova da Beira (PT)
- Hospital de Egas Moniz (PT)
- Centro Hospitalar de Lisboa Ocidental (PT)
- Instituto de Tecnología Química (ES)
- National Institute of Health Dr. Ricardo Jorge (PT)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- ARP Rheumatology
- Published
- 2024-12-31
- DOI
- https://doi.org/10.63032/prej7967
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00