Oral Microbiome Dysbiosis Is Associated With Precancerous Lesions and Disorders of Upper Gastrointestinal Tract: A Population-Based Study
Dysbiosis of saliva microbiota is linked to a broad spectrum of UGI disorders. However, microbiota dysbiosis in subgingival and buccal mucosa sites is specifically associated with the premalignant conditions such as Barrett's esophagus and gastric atrophy. Among oral sites, the subgingival microbiota shows more potential as a infectious biomarker for UGI cancers.
Authors
- Lars Agréus (ORCID: https://orcid.org/0000-0002-6026-9883)
- Michael Vieth (ORCID: https://orcid.org/0000-0002-4336-7721)
- Nicholas Joseph Talley (ORCID: https://orcid.org/0000-0003-2537-3092)
- Ulrika Zagai (ORCID: https://orcid.org/0000-0003-0807-5835)
- Anna Andréasson (ORCID: https://orcid.org/0000-0003-0203-7977)
- Amir Sohrabi (ORCID: https://orcid.org/0000-0001-5867-3636)
- Weimin Ye (ORCID: https://orcid.org/0000-0002-6859-4648)
- Fatemeh Sadeghi (ORCID: https://orcid.org/0000-0002-0018-2954)
Institutions
- Fujian Medical University (CN)
- Stockholm University (SE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Bayreuth Medical Center (DE)
- Karolinska Institutet (SE)
- University of Newcastle Australia (AU)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2024-12-31
- DOI
- https://doi.org/10.14309/ajg.0000000000003279
- Citations
- 11
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 6.30