Assessment of clinical and histopathological changes in leukoplakia using curcumin lozenges based on revised WHO criteria- A pilot study

The pilot study suggests curcumin lozenges may benefit leukoplakia patients, but the small sample size limits definitive conclusions. Larger studies are needed to confirm these findings and assess long-term efficacy. WHO 2022 criteria showed subjectivity and variability. Despite this, they were useful for identifying specific changes. To the best of our knowledge to date, no other study has validated these WHO 2022 features in repeated biopsies.