The Bifidogenic Effect of 2’Fucosyllactose Is Driven by Age-Specific Bifidobacterium Species, Demonstrating Age as an Important Factor for Gut Microbiome Targeted Precision Medicine
Age is an important factor in shaping the gut microbiome, with the dominant taxa and their metabolites changing over a lifetime. This divergence affects the response of the microbiota to therapeutics, demonstrated in this study using 2'FL. These results evidence the importance of screening across multiple age groups separately to provide granularity of how therapeutics impact the microbiome and, consequently, human health.
Authors
- Aurélien Baudot (ORCID: https://orcid.org/0009-0009-4872-6875)
- Jenni Firrman (ORCID: https://orcid.org/0000-0002-9586-5204)
- Stef Deyaert
- Marie Joossens (ORCID: https://orcid.org/0000-0001-8410-5528)
- Jonas Poppe (ORCID: https://orcid.org/0000-0002-8640-2101)
- Simon J. S. Cameron (ORCID: https://orcid.org/0000-0001-9570-135X)
- LinShu Liu (ORCID: https://orcid.org/0000-0003-3962-290X)
- Karley K. Mahalak (ORCID: https://orcid.org/0000-0002-8638-1718)
- Pieter Van den Abbeele (ORCID: https://orcid.org/0000-0002-1399-6332)
Institutions
- Queen's University Belfast (GB)
- Agricultural Research Service (US)
- United States Department of Agriculture (US)
- Ghent University (BE)
- Eastern Regional Research Center (US)
Publication Details
- Journal
- Nutrients
- Published
- 2024-12-31
- DOI
- https://doi.org/10.3390/nu17010151
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- U.S. Department of Agriculture