High-sensitivity detection of <i>Mycobacterium tuberculosis</i> DNA in tongue swab samples
Improved testing for tuberculosis (TB) is needed. Using a more accessible sample type than sputum may enable the detection of more cases, but it is critical that alternative samples be tested appropriately. Here, we describe two new, highly accurate methods for testing tongue swabs for TB DNA.
Authors
- Mark Hatherill (ORCID: https://orcid.org/0000-0003-3491-1809)
- Katherine A. Lochner (ORCID: https://orcid.org/0000-0003-4498-6433)
- Paul Yager (ORCID: https://orcid.org/0000-0003-1271-4599)
- Alaina M. Olson (ORCID: https://orcid.org/0000-0003-2384-5025)
- Kris M. Weigel (ORCID: https://orcid.org/0000-0003-3199-2148)
- Rachel C. Wood (ORCID: https://orcid.org/0009-0006-3931-8595)
- Gerard A. Cangelosi (ORCID: https://orcid.org/0000-0003-0006-6520)
- Alexander J. Yan (ORCID: https://orcid.org/0009-0005-4279-1036)
- Rane B. Dragovich
- Angelique K. Luabeya (ORCID: https://orcid.org/0000-0003-2008-0450)
Institutions
- University of Cape Town (ZA)
- University of Washington (US)
- South African Tuberculosis Vaccine Initiative (ZA)
Publication Details
- Journal
- Journal of Clinical Microbiology
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1128/jcm.01140-24
- Citations
- 12
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 4.64
Funders
- Bill and Melinda Gates Foundation
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases
- National Institute of Biomedical Imaging and Bioengineering