A Cost-Effective Two-Step Approach for Multi-Cancer Early Detection in High-Risk Populations
Large-scale screening inevitably leads to significant financial burdens on the healthcare system, which is a key factor constraining nationwide screenings. The two-step MCED approach not only maintains comparable performance but also substantially alleviates financial strains compared with the direct use of next-generation sequencing-based MCED tests for massive screenings.
Authors
- Yinyin Chang
- Shuaipeng Geng
- Shiyong Li (ORCID: https://orcid.org/0000-0003-0416-526X)
- Wei Wu (ORCID: https://orcid.org/0009-0007-6733-0986)
- Mao Mao (ORCID: https://orcid.org/0000-0002-8570-8571)
Institutions
- Yonsei University (KR)
- BioClinica (United States) (US)
- DermResearch (United States) (US)
Publication Details
- Journal
- Cancer Research Communications
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1158/2767-9764.crc-24-0508
- Citations
- 3
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.86