Contemporary Cytomegalovirus (CMV) Infections in Low‐Risk CMV Seronegative Recipients of Solid Organ Transplants From CMV Seronegative Donors (D−/R−): Time to Reexamine Donor CMV Serostatus
Early CMV infections in D-/R- SOTR are uncommon but associated with high morbidity. CMV transmission from organ donors with false negative CMV serology is an important source of early CMV infections in D-/R- SOTR. Clinicians should suspect and promptly report early CMV infections in D-/R- SOTR as potential donor-derived processes, regardless of donor and/or recipient transfusion histories. Reporting such cases is essential to promote broader investigations that may identify suboptimal donor CMV screening assays.
Authors
- Annette J. Schlueter (ORCID: https://orcid.org/0000-0003-2442-7079)
- Mark J. Lee
- Julia A. Messina (ORCID: https://orcid.org/0000-0001-6411-198X)
- Jennifer L. Saullo (ORCID: https://orcid.org/0000-0002-7684-431X)
- Madeleine R. Heldman (ORCID: https://orcid.org/0000-0002-9424-1870)
- Rachel Miller (ORCID: https://orcid.org/0000-0001-7387-1171)
Institutions
- University of Iowa (US)
- Duke University (US)
Publication Details
- Journal
- Clinical Transplantation
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1111/ctr.70073
- Citations
- 2
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.77