Canine Stem Cell-derived Exosomes for Lung Inflammation: Efficacy of Intratracheal<i>Versus</i>Intravenous Administration in an Acute Lung Injury Mouse Model
This study compared the effects of stem cell-derived exosomes on alleviating lung inflammation according to injection routes in an ALI mouse model. It was confirmed that direct injection of exosomes into the airway had a greater ability to alleviate lung inflammation than intravenous injection by polarizing M2 macrophages and increasing regulatory T cells.
Authors
- S. Kim (ORCID: https://orcid.org/0009-0000-8976-2455)
- Ga‐Hyun Lim (ORCID: https://orcid.org/0000-0001-7019-6246)
- Ju‐Hyun An (ORCID: https://orcid.org/0000-0002-3756-9482)
- Taesook Yoon
- You-Seok Kim (ORCID: https://orcid.org/0000-0001-8911-4685)
- Jisook Moon (ORCID: https://orcid.org/0000-0002-7044-4841)
- Hyuncheol Oh (ORCID: https://orcid.org/0000-0001-9394-4358)
Institutions
- Kangwon National University (KR)
- Ajou University (KR)
Publication Details
- Journal
- In Vivo
- Published
- 2024-12-31
- DOI
- https://doi.org/10.21873/invivo.13821
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea