Endo 180 participates in collagen remodeling of the periodontal ligament during orthodontic tooth movement
Force-induced Endo180 expression modulates collagen remodeling in PDL during OTM by upregulating COL III and downregulating COL I. This collagen reorganization facilitates efficient tooth movement, highlighting Endo180 as a potential therapeutic target to optimize orthodontic treatment outcomes.
Authors
- Yuetong Chen
- Nan Jiang (ORCID: https://orcid.org/0000-0002-0671-6822)
- Shengjie Cui (ORCID: https://orcid.org/0000-0003-0330-1530)
- Zhihe Zhao (ORCID: https://orcid.org/0000-0003-2955-1706)
- Yan Liu (ORCID: https://orcid.org/0000-0001-5531-2376)
- Liyuan Chen (ORCID: https://orcid.org/0000-0002-2837-0527)
- Min Yu (ORCID: https://orcid.org/0000-0001-7208-2197)
- Danqing He
- Zixin Li (ORCID: https://orcid.org/0009-0005-3425-5727)
- Huajie Yu
- Jiayi Song (ORCID: https://orcid.org/0009-0008-2741-5915)
Institutions
- King University (US)
- Peking University (CN)
- Peking University People's Hospital (CN)
- National Clinical Research (US)
- Stomatology Hospital (CN)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1186/s12903-024-05362-8
- Citations
- 2
- Primary Topic
- Protease and Inhibitor Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- National Natural Science Foundation of China
- Peking University