Impact of antiplatelet therapy on hemostatic plug formation in the setting of thrombocytopenia
Our experimental data suggests that for severe thrombocytopenia, single APT provides an appropriate balance of antithrombotic effect and limited bleeding, with clopidogrel demonstrating a greater antithrombotic effect but slightly increased bleeding compared with aspirin.
Authors
- Wolfgang Bergmeier (ORCID: https://orcid.org/0000-0002-1211-8861)
- Robert H. Lee (ORCID: https://orcid.org/0000-0001-9871-0593)
- Abigail Ballard-Kordeliski (ORCID: https://orcid.org/0000-0002-7773-1093)
- Summer R Jones
Institutions
- University of North Carolina at Chapel Hill (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1016/j.rpth.2024.102672
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute