Tumor necrosis factor receptor-associated factor 5 enhances perianal fistulizing Crohn’s disease through epithelial–mesenchymal transition
The development of PFCD was associated with EMT, and TRAF5 was a key gene of PFCD. Knocking down TRAF5 alleviated the EMT promotion of PFCD, indicating that TRAF5 drove the development of PFCD through EMT.
Authors
- Youran Li (ORCID: https://orcid.org/0000-0003-3396-4132)
- Hairui Gao
- Xiaomei Sun
- Yunfei Gu (ORCID: https://orcid.org/0000-0003-2979-0934)
- Lu Lu (ORCID: https://orcid.org/0000-0002-0960-1529)
- Qianqian Wang (ORCID: https://orcid.org/0009-0004-9065-555X)
Institutions
- Qingdao University (CN)
- Nanjing University of Chinese Medicine (CN)
- Affiliated Hospital of Qingdao University (CN)
- Jiangsu Province Hospital (CN)
- Shaoxing People's Hospital (CN)
Publication Details
- Journal
- CytoJournal
- Published
- 2024-12-31
- DOI
- https://doi.org/10.25259/cytojournal_148_2024
- Citations
- 2
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.10