The Functional Characterization of Venous Thromboembolic Disease (FUVID) study: rationale, design, and methods of a prospective, observational, multicenter study to evaluate mechanisms of exercise intolerance and dyspnea following pediatric pulmonary
The FUVID study will investigate the relationship between symptoms (exercise intolerance and exertional dyspnea) and multiple mechanisms-hemodynamic, ventilatory, or peripheral/muscle-within the same patient at rest, submaximal exercise (simulating activities of daily living), and maximal exercise using objective measures. It will provide new evidence for selecting patients for long-term follow-up, including psychological sequelae, after PE, the modalities this follow-up should include, and the findings interpreted as indicating functional limitations after PE.
Authors
- Gary Woods (ORCID: https://orcid.org/0000-0002-0921-0974)
- Rukhmi Bhat (ORCID: https://orcid.org/0000-0002-1700-4804)
- Jéssica Garcia (ORCID: https://orcid.org/0000-0003-2627-5531)
- Kerry Hege
- Sarah O Brien
- Joshua S. Greer (ORCID: https://orcid.org/0000-0002-1423-6781)
- Rohith Jesudas (ORCID: https://orcid.org/0000-0002-9481-2581)
- Neil A. Goldenberg (ORCID: https://orcid.org/0000-0003-0335-101X)
- Bryce N. Balmain (ORCID: https://orcid.org/0000-0002-2642-7083)
- Robert F. Mattrey (ORCID: https://orcid.org/0000-0002-4813-1523)
- Shelley E. Crary (ORCID: https://orcid.org/0000-0002-5133-9624)
- Osman Khan (ORCID: https://orcid.org/0000-0002-4386-4015)
- Tony G. Babb
- Benjamin G. Levine (ORCID: https://orcid.org/0000-0002-0356-0738)
- Riten Kumar (ORCID: https://orcid.org/0000-0001-8004-4190)
- Marcela Torres (ORCID: https://orcid.org/0000-0002-7356-4910)
- Madhvi Rajpurkar (ORCID: https://orcid.org/0000-0002-5884-6776)
- Sharon Primeaux (ORCID: https://orcid.org/0009-0000-7358-8210)
- Hilary Whitworth (ORCID: https://orcid.org/0000-0002-5323-7023)
- Jimin Ren (ORCID: https://orcid.org/0000-0001-7946-8447)
- Angela C. Weyand (ORCID: https://orcid.org/0000-0003-2595-8541)
- Frederikus Albertus Klok (ORCID: https://orcid.org/0000-0001-9961-0754)
- Hope P. Wilson (ORCID: https://orcid.org/0000-0001-8904-3338)
- Julie Jaffray
- Ruchika Sharma (ORCID: https://orcid.org/0000-0002-3157-2445)
- Kisha A Beg
- Manal AlQahtani
- Cristina Tarango (ORCID: https://orcid.org/0000-0002-0283-9972)
- Lauren E. Amos (ORCID: https://orcid.org/0000-0002-3357-898X)
- Michael D. Nelson (ORCID: https://orcid.org/0000-0002-3232-8639)
- Ayesha N Zia (ORCID: https://orcid.org/0000-0003-3283-0415)
- Clay T. Cohen (ORCID: https://orcid.org/0000-0001-6819-4049)
- Beverly A. Schaefer (ORCID: https://orcid.org/0000-0001-5427-9666)
- Mary Dang (ORCID: https://orcid.org/0000-0003-0187-4335)
- Byoung Geun Han (ORCID: https://orcid.org/0000-0002-3246-2993)
- Christoph Male (ORCID: https://orcid.org/0000-0002-4989-6421)
- Marisol Betensky (ORCID: https://orcid.org/0000-0001-6725-3035)
- Martha M. Pacheco
- Jonathan A. Bernstein (ORCID: https://orcid.org/0000-0002-3476-1196)
- Song Zhang (ORCID: https://orcid.org/0000-0002-0245-9355)
- Tarique Hussain (ORCID: https://orcid.org/0000-0003-4091-992X)
- Sonja Stutzman (ORCID: https://orcid.org/0000-0002-8902-2067)
- Kendra Malone
- Deseray Sida
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Women & Children's Hospital of Buffalo (US)
- Roswell Park Comprehensive Cancer Center (US)
- St. Jude Children's Research Hospital (US)
- Nationwide Children's Hospital (US)
- Children's Mercy Hospital (US)
- Children's Hospital of Philadelphia (US)
- Johns Hopkins University (US)
- Emory University (US)
- Central Michigan University (US)
- The University of Texas at Arlington (US)
- University of Michigan (US)
- University of Arkansas Medical Center (US)
- Leiden University Medical Center (NL)
- Riley Hospital for Children (US)
- University of Alabama at Birmingham (US)
- Rady Children's Hospital-San Diego (US)
- Cook Children's Medical Center (US)
- Johns Hopkins All Children's Hospital (US)
- Cook Children's Health Care System (US)
- Michigan Medicine (US)
- Children's Hospital of Oklahoma (US)
- St. Luke's Children's Hospital (US)
- Lurie Children's Hospital (US)
- Advanced Imaging Research (United States) (US)
- Institute for Exercise and Environmental Medicine (US)
- Texas Children's Hospital (US)
- Children's Cancer Center (US)
- St. Luke's Mountain States Tumor Institute (US)
- University Cancer and Blood Center (US)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Medical University of Vienna (AT)
- University of Arkansas for Medical Sciences (US)
- Penn State Milton S. Hershey Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1016/j.rpth.2024.102669
- Citations
- 2
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- American Heart Association
- University of Texas Southwestern Medical Center
- National Institutes of Health
- National Heart, Lung, and Blood Institute