Assessing the relationship between liver and spleen volumes in patients with liver cirrhosis using the Cavalieri principle on cross-sectional images
In the early stages of liver cirrhosis, hepatomegaly is observed, while in the later stages, enlargement of the spleen is observed due to shrinkage of the liver and increased pressure in the portal circulation. This study examined liver and spleen volumes and their proportional relationship to each other in healthy controls (HC) and patients with liver cirrhosis (LC) using computed tomography (CT) images. CT images of 52 LC (26 females, 26 males) and 52 HC (26 females, 26 males) aged 18 to 85 years were used. Liver and spleen volumes and spleen/liver+spleen volume ratio were calculated using the Cavalieri principle. Volume and ratio data were compared between HC and LC. In addition, volumes and ratios were evaluated according to the disease classes in patients. Liver volume was larger in LC (1488.9±502.3 cm3) than in HC (1321.8±277.1 cm3) (p=0.038). Spleen volume was also larger in LC (676.8±347.02 cm3) than in HC (249.37±101.16 cm3) (p
Authors
- Merve Nur Özgen (ORCID: https://orcid.org/0000-0002-1134-5309)
- Abdurrahman Şahin (ORCID: https://orcid.org/0000-0001-5477-9492)
- Ruken Yüksekkaya (ORCID: https://orcid.org/0000-0003-0289-6704)
- Bünyamin Şahin (ORCID: https://orcid.org/0000-0001-8538-8443)
Institutions
- Ondokuz Mayıs University (TR)
- Tokat Gaziosmanpaşa Üniversitesi (TR)
- Hitit Üniversitesi Çorum Eğitim ve Araştırma Hastanesi (TR)
Publication Details
- Journal
- DergiPark (Istanbul University)
- Published
- 2024-09-08
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00