Formulation development of ranitidine with nanoparticles for enhancement of efficacy

In the current world, various forms of cardiovascular diseases such as hypertension, stroke, heart failure, and arrhythmias— along with other diseases —critically impact a person’s life and overall well-being. It is becoming a global challenge to overcome these diseases (Li 2023). In 2021 the approximate number of patients suffering from cardiovascular diseases globally was 20.5 million and the predicted cardiovascular death rate of any given year over the ensuing hundred years in any country was estimated to be about 1.05% (Oleg Gaidai 2023b). Symptoms of cardiovascular diseases vary from patient to patient (Corrine Y. Jurgens 2022) and can be caused by various factors such as smoking, diet, unhealthy lifestyle, obesity, and diabetes. (Dahlöf 2010, R. Nangia 2016). Coronary artery disease most commonly arises as a result of cholesterol buildup in the coronary artery or due to damage of the arterial lining causing a decrease in blood supply to the heart (Peter Libby 2005, Valentin Fuster 1992).