Neuroendocrine tumour of a larynx in 70-year-old man: a rare entity and a diagnostic challenge

Neuroendocrine tumours of the larynx are rare yet neuroendocrine tumors is the second most common larynx tumour. According to the World Health Organization (WHO) 2022 classification, neuroendocrine tumours (NET) can be classified into well-differentiated, moderately differentiated and poorly differentiated. Well-differentiated NETs (typical carcinoids) of the larynx are rare and largely published as case reports. We present a case of a 70-year-old male with a history of hoarseness of voice for 1 year. Grossly, the tumour was globular and encapsulated. Based on histopathological features and immunohistochemistry results, the final diagnosis of a well-differentiated Neuroendocrine tumour was rendered. For carcinoid tumours of the larynx, conservative surgical resection is the preferred treatment without elective neck dissection. This tumour has a favourable prognosis, rare recurrences, and minimal metastasis.

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Journal
International Journal of Research in Medical Sciences
Published
2024-12-31
DOI
https://doi.org/10.18203/2320-6012.ijrms20244146
Primary Topic
Neuroendocrine Tumor Research Advances
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article
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article

Neuroendocrine tumour of a larynx in 70-year-old man: a rare entity and a diagnostic challenge

Nida Shabbir, Sumaira Qayoom, Ajay Singh, Manish Chandra
International Journal of Research in Medical Sciences
Neuroendocrine Tumor Research Advances
article

Neuroendocrine tumour of a larynx in 70-year-old man: a rare entity and a diagnostic challenge

Nida Shabbir, Sumaira Qayoom, Ajay Singh, Manish Chandra
article en

Abstract

Neuroendocrine tumours of the larynx are rare yet neuroendocrine tumors is the second most common larynx tumour. According to the World Health Organization (WHO) 2022 classification, neuroendocrine tumours (NET) can be classified into well-differentiated, moderately differentiated and poorly differentiated. Well-differentiated NETs (typical carcinoids) of the larynx are rare and largely published as case reports. We present a case of a 70-year-old male with a history of hoarseness of voice for 1 year. Grossly, the tumour was globular and encapsulated. Based on histopathological features and immunohistochemistry results, the final diagnosis of a well-differentiated Neuroendocrine tumour was rendered. For carcinoid tumours of the larynx, conservative surgical resection is the preferred treatment without elective neck dissection. This tumour has a favourable prognosis, rare recurrences, and minimal metastasis.

International Journal of Research in Medical SciencesVol. 13(1)
King George's Medical University (IN)
Good health and well-being
Openalex Percentile: Top 63%
Neuroendocrine Tumor Research Advances
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Neuroendocrine tumour of a larynx in 70-year-old man: a rare entity and a diagnostic challenge — Nida Shabbir, Sumaira Qayoom, et al. · International Journal of Research in Medical Sciences (2024) | TGRS Research Map | TGRS