Evaluation of the impact of COVID-19 pandemic on hospital admission related to common infections: Risk prediction models to tackle antimicrobial resistance in primary care
A substantial variation in hospital admission risks between infections and patient groups was found. Antibiotics appeared more effective in preventing infection-related complications with LRTI and UTI, but not URTI. While this study has several limitations, the results indicate that a focus on risk-based antibiotic prescribing could help tackle AMR in primary care.
Authors
- Kieran Hand (ORCID: https://orcid.org/0000-0002-3834-2415)
- Darren Mark Ashcroft (ORCID: https://orcid.org/0000-0002-2958-915X)
- Jon Massey (ORCID: https://orcid.org/0000-0002-2497-4040)
- Tjeerd van Staa (ORCID: https://orcid.org/0000-0001-9363-742X)
- Seb Bacon (ORCID: https://orcid.org/0000-0002-6354-3454)
- Amir Mehrkar (ORCID: https://orcid.org/0000-0002-2098-1278)
- Ya-Ting Yang (ORCID: https://orcid.org/0000-0001-5880-4827)
- Louis Fisher (ORCID: https://orcid.org/0000-0002-0295-3812)
- Victoria Palin (ORCID: https://orcid.org/0000-0002-0851-8619)
- Simon Watts (ORCID: https://orcid.org/0000-0002-2183-8668)
- Ben Goldacre (ORCID: https://orcid.org/0000-0002-5127-4728)
- Xiaomin Zhong
- Ali Fahmi (ORCID: https://orcid.org/0000-0002-1661-4475)
- Brian MacKenna
Institutions
- Manchester Academic Health Science Centre (GB)
- University of Manchester (GB)
- University of Oxford (GB)
- North West Ambulance Service NHS Trust (GB)
- NHS England
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1371/journal.pone.0311515
- Citations
- 2
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 0.60
Funders
- Laura and John Arnold Foundation
- Wellcome Trust
- UK Research and Innovation
- National Institute for Health and Care Research
- Department of Health and Social Care
- British Lung Foundation
- Asthma and Lung UK
- Public Health England
- NIHR Greater Manchester Patient Safety Translational Research Centre
- Patient Safety Translational Research Centre
- Medical Research Council
- NIHR Oxford Biomedical Research Centre
- National Institute for Health and Care Research Applied Research Collaboration Oxford and Thames Valley