Should We Adopt Increased Dilutions for Indirect Immunofluorescence in Pediatric Anti-Centromere Antibody Testing? Insights from a Three-Year Retrospective Study
This study highlights the diagnostic value of higher IIF dilution levels (≥1/640) in improving ACA detection and SARD diagnosis in pediatric patients. Incorporating complementary diagnostic tools, such as immunoblot testing, can enhance diagnostic accuracy. These findings support adopting higher IIF cutoff levels in clinical practice for pediatric populations.
Authors
- Miray Karakoyun (ORCID: https://orcid.org/0000-0002-6533-6256)
- Seyfi Durmaz (ORCID: https://orcid.org/0000-0001-9756-7764)
- Gülçin Aytaç (ORCID: https://orcid.org/0000-0003-3821-5288)
- Güzide Aksu (ORCID: https://orcid.org/0000-0003-2714-0903)
- Rüçhan Sertöz (ORCID: https://orcid.org/0000-0002-5321-4710)
- Mehmet Soylu (ORCID: https://orcid.org/0000-0002-9145-1506)
- Raziye Burcu Taşkın (ORCID: https://orcid.org/0000-0003-1734-8102)
Institutions
- Ege University (TR)
Publication Details
- Journal
- Children
- Published
- 2024-12-28
- DOI
- https://doi.org/10.3390/children12010036
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ege Üniversitesi