Biometrology and standard: Research and application

In the 21st century, with the rapid development of biotechnology and bio-industry, coupled with growing challenges to human survival and health, the need for accurate and reliable biological data has become increasingly pronounced. It has not only given rise to the new discipline of biometrology but has also drawn global attention to its standards and biological reference materials (BRMs). Under the new circumstances, the volume of data from bioanalysis and measurement is increasing at an exponential rate. Biometrology plays a particularly crucial role in guaranteeing the validity of biological data. With over 20 years of development, the biometrology systems have been established and continuously enhanced through research efforts in China. Research and application efforts in nucleic acid and protein measurement technology and standard, along with the development of standard systems, have been initiated for the aim to establish and maintain the biomeasurement standard. These technologies have been used in many fields, including the detection nucleic acids and proteins in transgenic products, in vitro diagnostic, virus detection, and quarantine measures, facilitating the acquisition of accurate values and enabling traceability. Biometrology and standard research is also facing with challenges for these demands.