Integrated bioinformatics and multi-omics to investigate the mechanism of Rhododendron molle Flos-induced hepatotoxicity
This study comprehensively identified the toxic components, upstream targets, and downstream metabolites of RMF-induced liver toxicity, providing a basis for evaluating and monitoring liver function in patients during clinical application.
Authors
- Keqing Han
- Wenhui Wu (ORCID: https://orcid.org/0000-0001-8962-4693)
- Lijuan Wang (ORCID: https://orcid.org/0009-0007-5575-3164)
- Qiang Ran
- Min Yang (ORCID: https://orcid.org/0000-0002-3827-5961)
- Xiaohong Guo (ORCID: https://orcid.org/0009-0008-5004-8244)
- Juan Chen (ORCID: https://orcid.org/0000-0002-0425-5348)
- Yanyan Li (ORCID: https://orcid.org/0000-0002-3059-7237)
- Mengjun Huang (ORCID: https://orcid.org/0000-0002-3341-8011)
- Xia Liu (ORCID: https://orcid.org/0000-0003-1616-8222)
Institutions
- Chongqing University (CN)
- Shanxi Medical University (CN)
- Shaanxi Provincial People's Hospital (CN)
- Shanxi Provincial People’s Hospital (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1016/j.jep.2024.119308
- Citations
- 10
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 3.61