Genetic Insights Into the Role of Cathepsins in Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis: Evidence From Mendelian Randomization Study
Our study provides new genetic insights into the role of cathepsin H in AD and cathepsin B in PD. However, our findings need to be further validated in a wider population, and future research should explore the potential mechanisms of cathepsins in these diseases in order to provide a basis for the development of new therapeutic strategies.
Authors
- Hua Xue (ORCID: https://orcid.org/0009-0002-8366-6977)
- Yaxin Li (ORCID: https://orcid.org/0000-0002-4271-8569)
- Yan‐Hong Jiang (ORCID: https://orcid.org/0000-0003-4366-0503)
- Wenhui Fan (ORCID: https://orcid.org/0000-0002-1018-0258)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1002/brb3.70207
- Citations
- 4
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.31