Mean Nocturnal Baseline Impedance May Be Greater Than 2500 Ohms in Chinese Patients With <scp>GERD</scp>
Approximately one-third of Chinese GERD patients have an MNBI > 2500 Ω. The thresholds of MNBI for supporting or ruling out GERD in the Chinese population should be adjusted. MNBI values are independently predicted by the severity of supine acid reflux and the LES resting pressure. GERD patients with mild supine acid reflux may still exhibit normal MNBI levels. Patients with lower MNBI values tend to show better responses to PPI therapy.
Authors
- Junying Xu (ORCID: https://orcid.org/0000-0001-6400-0606)
- Xuelian Xiang (ORCID: https://orcid.org/0000-0001-6266-0336)
- Dongke Wang (ORCID: https://orcid.org/0000-0002-1497-4346)
- Xiaohao Zhang (ORCID: https://orcid.org/0000-0002-8916-8592)
- Xiaohua Hou (ORCID: https://orcid.org/0000-0002-4777-7920)
- Chaofan Duan (ORCID: https://orcid.org/0009-0008-0917-7407)
Institutions
- Union Hospital (HK)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1111/nmo.14986
- Citations
- 1
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.46
Funders
- National Natural Science Foundation of China