Advancing precision medicine in esophageal squamous cell carcinoma using patient-derived organoids
Organoid biobanks were established across multiple institutes to facilitate PDOs-based functional precision medicine. The findings demonstrate that this framework offers robust predictive value in clinical settings, enhances precision therapeutics, and advances drug discovery for esophageal cancer.
Authors
- Pengju Zhang (ORCID: https://orcid.org/0000-0002-6643-0017)
- Ziyao Liu (ORCID: https://orcid.org/0000-0002-5332-6333)
- Yi Hu (ORCID: https://orcid.org/0000-0002-1408-9531)
- Wenyan Guan (ORCID: https://orcid.org/0000-0002-4304-2417)
- Bing Liu (ORCID: https://orcid.org/0000-0002-7313-6924)
- Wei Ren (ORCID: https://orcid.org/0000-0003-2573-8469)
- Zhiwen Li (ORCID: https://orcid.org/0009-0000-1303-0071)
- Yiqiang Chen (ORCID: https://orcid.org/0000-0001-6814-8181)
- Jian He (ORCID: https://orcid.org/0000-0002-5142-6357)
- Weifeng Tang (ORCID: https://orcid.org/0000-0002-8261-8116)
- Yuqing Han (ORCID: https://orcid.org/0009-0005-2446-4939)
- Yudong Qiu (ORCID: https://orcid.org/0009-0007-8227-9322)
- Hongping Zheng
- Siyuan Liu (ORCID: https://orcid.org/0009-0009-2138-5740)
- Shitong Shen (ORCID: https://orcid.org/0000-0002-8960-119X)
- Jingjing Li (ORCID: https://orcid.org/0009-0001-9385-0535)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Peking University (CN)
- Wenzhou Medical University (CN)
- Peking University Cancer Hospital (CN)
- Nanjing Drum Tower Hospital (CN)
- Jiangsu Cancer Hospital (CN)
- Zhejiang Taizhou Hospital (CN)
- Shanghai Institute of Pharmaceutical Industry (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1186/s12967-024-05967-1
- Citations
- 7
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 1.98
Funders
- National Natural Science Foundation of China
- China Scholarship Council
- Nanjing Drum Tower Hospital