Investigations of insulin resistance in obese dogs

The aim of the study was to investigate insulin resistance in overweight and obese dogs. Obesity is excessive fat accumulation in the body and is defined as being 30% above the ideal body weight. In the study, a total of 30 dogs were divided into 3 equal groups: ideal weight, overweight and obese. Fasting serum samples were collected and used to measure insulin (INS) and asprosin (ASP) levels using dog-specific ELISA kits. Glucose (GLU) and fructosamine (FRU) were also determined using biochemistry analyzer and Idexx test kits, respectively. HOMA-IR (homeostasis model assessment of insulin resistance), HOMA-β% (homeostasis model assessment of β cell function) and insulin-glucose ratio (IGR) were calculated using glucose and insulin values. In the study, ASP (p