Metabolomic Signatures Highlight Fiber-Degrading Bacteroides Species in Mediterranean Diet Response Among Ulcerative Colitis
High adherence to an MDP is associated with beneficial metabolite changes associated with reducing inflammation in UC. In addition, fiber-degrading microbes abundant before dietary intervention played a role in the responsiveness to the MDP. This work lays the groundwork for developing a metabolic signature associated with the MDP to develop personalized nutrition strategies for UC prevention and treatment. ClinicalTrials.gov Number: NCT03053713.
Authors
- Maitreyi Raman (ORCID: https://orcid.org/0000-0002-9129-3632)
- Jiayu Ye (ORCID: https://orcid.org/0000-0002-1704-6780)
- Sanjoy Ghosh (ORCID: https://orcid.org/0000-0002-2407-5782)
- Natasha Haskey (ORCID: https://orcid.org/0000-0001-7349-9445)
- Jessica Josephson (ORCID: https://orcid.org/0000-0003-2216-376X)
Institutions
- University of Calgary (CA)
- Palo Alto University (US)
- Stanford Medicine (US)
- Okanagan University College (CA)
- Stanford University (US)
Publication Details
- Journal
- Gastro Hep Advances
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1016/j.gastha.2024.100606
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Canadian Association of Gastroenterology
- Crohn's and Colitis Canada
- Canadian Institutes of Health Research