Palladium-Catalyzed Intramolecular C–H Amination via Oxidative Coupling on Indole Derivatives: Access to 11<i>H</i>-Benzo[4,5]imidazo[1,2-<i>a</i>]indoles
A novel palladium-catalyzed intramolecular C-H amination via oxidative coupling exploiting inactivated N-substituted aryl amines on indoles for the one-pot synthesis of novel 11<i>H</i>-benzo[4,5]imidazo[1,2-<i>a</i>]indole derivatives is reported. The optimized reaction conditions accommodated a wide range of electronic variations on both the indole and the pendant aryl amine ring, resulting in products with good to excellent yields.
Authors
- Vinod D. Chaudhari (ORCID: https://orcid.org/0000-0003-1785-9287)
- Simran Kaur (ORCID: https://orcid.org/0000-0002-8068-921X)
- Yogesh Sharma
- Subash Chandra Sahoo (ORCID: https://orcid.org/0000-0003-2557-1937)
- Hariprasath Kandhasamy
Institutions
- Institute of Microbial Technology (IN)
- Panjab University (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1021/acs.orglett.4c04563
- Citations
- 4
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.00
Funders
- Council of Scientific and Industrial Research, India
- University Grants Commission