Histologic evidence of neutrophil extracellular traps and fibrin(ogen) deposition in liver biopsies from patients with inflammatory liver disease
In contrast to experimental studies, we demonstrated minimal intrahepatic fibrin(ogen) deposition in different types of human inflammatory liver disease. Histologic evidence for intrahepatic NETs was common and most pronounced in acute ASH and IRI and was associated with platelet deposition and disease severity.
Authors
- William E. Bernal (ORCID: https://orcid.org/0000-0002-6508-3287)
- Fien A. von Meijenfeldt (ORCID: https://orcid.org/0000-0003-0274-2414)
- A. C. L. Pacheco
- Ton Lisman (ORCID: https://orcid.org/0000-0002-3503-7140)
- Yoh Zen (ORCID: https://orcid.org/0000-0001-8370-6508)
Institutions
- University Medical Center Groningen (NL)
- King's College Hospital (GB)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1016/j.rpth.2024.102666
- Citations
- 5
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Stichting De Cock-Hadders