Intrahepatic levels of microbiome-derived hippurate associates with improved metabolic dysfunction-associated steatotic liver disease
Altogether, our results further highlight hippurate as a mechanistic marker of metabolic health, by its ability to improve metabolic homeostasis as a postbiotic candidate.
Authors
- Bart Staels (ORCID: https://orcid.org/0000-0002-3784-1503)
- François Pattou (ORCID: https://orcid.org/0000-0001-8388-3766)
- Yasmina Kahoul (ORCID: https://orcid.org/0000-0002-5587-4958)
- Philippe Froguel (ORCID: https://orcid.org/0000-0003-2972-0784)
- Marc‐Emmanuel Dumas (ORCID: https://orcid.org/0000-0001-9523-7024)
- Amélie Bonnefond (ORCID: https://orcid.org/0000-0001-9976-3005)
- Audrey Leloire
- Philippe Lefèbvre (ORCID: https://orcid.org/0000-0002-9366-5129)
- Robert Caïazzo (ORCID: https://orcid.org/0000-0001-5383-0540)
- Francesc Puig‐Castellví (ORCID: https://orcid.org/0000-0003-1064-9586)
- Violeta Raverdy (ORCID: https://orcid.org/0000-0001-5754-2028)
- Romina Pacheco‐Tapia (ORCID: https://orcid.org/0000-0002-4694-3456)
- Souhila Amanzougarene
- Nicolas Gambardella
- Guillaume Lassailly (ORCID: https://orcid.org/0000-0002-6955-244X)
- Frédérik Oger (ORCID: https://orcid.org/0000-0003-0006-5835)
- Maxime Deslande
- Bénédicte Toussaint
- Mehdi Derhourhi (ORCID: https://orcid.org/0000-0001-5020-5379)
- Petros Andrikopoulos (ORCID: https://orcid.org/0000-0002-1555-3498)
- Nawel Zaïbi
- Inés Castro-Dionicio
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Institut Pasteur de Lille (FR)
- Imperial College London (GB)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2024-12-31
- DOI
- https://doi.org/10.1016/j.molmet.2024.102090
- Citations
- 5
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.93
Funders
- Université de Lille
- National Institute for Health and Care Research
- Diabetes UK
- European Commission
- Agence Nationale de la Recherche
- Conseil Régional Hauts-de-France
- Medical Research Council
- NIHR Imperial Biomedical Research Centre
- CHIST-ERA