DIAGNOSTIC OF ENDOMETRIOSIS BY METHODS OF DIFFUSE INTROSCOPY THESIOGRAM OF DEHYDRATED BLOOD SERUM FILMS

This article contains the following results of research on endometriosis diagnosis of scattering dehydrated films of blood serum by the methods of diffuse Mueller-matrix endoscopy. The aim of the study. To assess the effectiveness of differential diagnosis of endometriosis using diffuse Muller-matrix endoscopy of scattering dehydrated films of blood serum. Material and methods. Three groups of samples were studied: blood serum of patients with tubal infertility – control group 2.1-68 samples; blood serum of patients with endometriosis – research group 2.2-59 samples; blood serum after treatment of patients with endometriosis – experimental group 2.3-59 samples. Research results. The analysis of the obtained statistical analysis data revealed the adequacy of the prognostic script of changes in the polycrystalline structure of scattering dehydrated films of blood serum: for patients with endometriosis, there is a significant decrease in the magnitude of fluctuations of linear birefringence due to the destruction of tertiary and quaternary serum proteins; samples of scattering dehydrated blood serum films from a group of patients after treatment are characterized by an increase in the level of fluctuations in the linear birefringence of supramolecular protein networks. Conclusion. Therefore, the application of the technique of diffuse Müller-matrix introscopy of supramolecular polycrystalline networks of the main blood serum proteins (albumin and globulin) made it possible to identify a set of new diagnostic markers that provide an excellent level of early diagnosis of endometriosis, as well as control of the effectiveness of its treatment under conditions of strong scattering of laser radiation in the of experimental samples.