Optimizing Microneutralization and IFN-γ ELISPOT Assays to Evaluate Mpox Immunity
Our newly developed microneutralization test has a good correlation with PRNT. UV-inactivated mpox is an appropriate antigen for the ELISPOT assay that measures mpox cross-reactive T cells. These assays will be useful in future mpox vaccine studies.
Authors
- Krystal A. Meza
- Yinyi Yu
- Getahun Abate (ORCID: https://orcid.org/0000-0002-7825-2422)
- Daniel F. Hoft (ORCID: https://orcid.org/0000-0002-8921-4093)
- Sharon E. Frey (ORCID: https://orcid.org/0009-0008-6313-4053)
- Azra Blazevic
- Anna Jaunarajs
- Chase G. Colbert
Institutions
- Emmes (United States) (US)
- Saint Louis University (US)
Publication Details
- Journal
- Vaccines
- Published
- 2024-12-31
- DOI
- https://doi.org/10.3390/vaccines13010027
- Citations
- 1
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 0.29